Antioxidant potential, biochemical activity and hypoglycemic effects of R. obtusifolius L. seed extracts used in Armenian traditional medicine

The diversity of plants in Armenia is due to the singularity natural environment. However, biochemical activity these has not been studied well. goal was investigate biological activities as well antihyperglycemic properties Rumex obtusifolius L. rabbits with hyperglycemia. According obtained data, R. extracts possessed high antioxidant chemical-based tests. GS/MS analysis its methanol allowed identification several compounds, which could have contribution on activities. sub-cytotoxic concentration investigated extract 10 mgmL -1 Murine microglial BV-2 WT cell lines. Oral administration ethanol showed significant effect hyperglycemia, reducing fasting glucose levels (57.3%, p<0.05) and improving tolerance. These findings suggest that be source new biologically active compounds recommended for treatment diabetes mellitus.